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On submitting a manuscript, whether an article or a letter, authors become responsible for disclosing all financial and personal relationships that could have an impact on the manuscript. They are obliged to disclose all sources of funding, including their own or private resources. To avoid uncertainty authors must explicitly state whether a potential conflict exists or not. This must be on the page following the title page. If necessary, full details must be given in a letter accompanying the manuscript. Authors must identify people who helped them with writing or otherwise, and state how such co-operation was financed. Investigators must reveal potential conflicts to study participants and must indicate in their manuscript whether they did so or not.